Alternative & Complimentary Therapies, December 2006. Mueller, Elizabeth A., and Patrick M. Schlievert. May people ask, why dont I just take coconut oil?. (A 15 pound animal = 1/10, or 8 pellets a day.) "The most effective antimicrobial compounds against all morphological forms of the two tested Borrelia sp. for the As a result, there are no dosage guidelines available, and the limited amount of research does not allow scientists to formulate an appropriate range of doses. The antibiotics included penicillin, oxacillin, and vancomycin. You can learn more about how we ensure our content is accurate and current by reading our. People say it increases their immune response, making them more resilient to bacterial, viral and fungal infections. I ordered some l-lysine and monolaurin (lauricidin) figuring Id give them a shot. Click on a box below to learn more about each insulin product. Consider some of the products located on this external site: Shop Monolaurin. Use Alphagan (Ophthalmic) exactly as directed on the label, or as prescribed by your doctor. Surg Infect (Larchmt). 1977 Sep;12(9):753-9. The recommended dose is one drop of ALPHAGAN P in the affected eye (s) three times daily, approximately 8 hours Then their health would begin to suffer - while those on native diets stayed healthy! These include several species of ringworm. Been dealing with EBV for about 14 months now. This prevents the virus from attaching and entering host cells, stopping infection and replication. Human milk fatty acid composition from nine countries varies most in DHA. Looking to try monolaurin? child is about 1/2 the average weight of an adult, so 1/2 the dosage. Delivery of Monolaurin (Capsule vs. Pellets vs. Powder): Pellets may not fully digest, and power tastes way too soapy / bitter. Researchers hypothesize that monolaurin incorporates itself into the cell membrane of gram-positive bacteria and destroys them by breaking down the cell membrane. Source: Thormar H, Isaacs CE, Brown HR, Barshatzky MR, Pessolano T. Inactivation of Enveloped Viruses and Killing of Cells by Fatty Acids and Monoglycerides. Researchers are investigating if monolaurin may inactivate or destroy various fungi and yeasts. without the wasted fillers and materials in capsules. epinephrine ophthalmic, latanoprost ophthalmic, timolol ophthalmic, pilocarpine ophthalmic, brimonidine ophthalmic, Lumigan, Combigan. Monolaurin - 500mg, Astragalus - 50mg, Beta Glucan - 50mg, Cat's Claw - 50mg, Olive Leaf - 50mg Directions As a dietary supplement, adults should take one (1) capsule daily or as recommended by a healthcare professional. The high activity of monoglycerides against H. pylori suggests that they may be useful as active ingredients in pharmaceutical formulations. A generally accepted dosage range is 1 -3 capsules 2 - 3 times daily (1800mg to 5400mg), but some customers prefer lower or The dose can be increased to 3.0 grams once or twice daily thereafter. Note that each number in parentheses [1, 2, 3, etc.] It should be swallowed, No herx. If one tablespoon of coconut oil were converted to 50% Monolaurin, you would need to take 6.5 teaspoons of coconut oil to achieve the amount of Monolaurin in one 600mg capsule (assuming one teaspoon of coconut oil is 0.924 g/cm3 [grams per cubic centimeter] is approximately 184.8 milligrams). Some scientsts believe that monolaurin may help fight microbesincluding bacteria, yeast, and parasitesbut their experiments are limited to cells and lab animals. However, 50% of mice given vancomycin and monolaurin daily survived for 30 days [5]. Coconut oil naturally contains around 40-50% lauric acid, the principal compound used to make monolaurin. Candida albicans is a common fungal pathogen that lives in the gut, mouth, genitals, urinary tract, and skin. Label (Claims, Formatting, and Research): Always look for proper citations, label formatting, and research when selecting a monolaurin brand, as this demonstrates FDA compliance and a well-managed operation. One teaspoon of our monolaurin has3,000 mg! Animal research indicates that the intestinal parasites Giardia lamblia and Entamoeba histolytica may respond to a combination of metronidazole (an anti-parasitic drug) and monolaurin [46]. Journal of Food Safety 4:1-12 (1982), Goc, A., Niedzwiecki, A. and Rath, M. (2015), In vitro evaluation of antibacterial activity of phytochemicals and micronutrients against Borrelia burgdorferi and Borrelia garinii. When choosing monolaurin as a dietary supplement, care should be taken to find a trusted and established brand. More research is needed [45]. [Ref # 27], Delivery: Levels of lauric acid and other acids including myristic, alpha-linolenic, arachidonic, and eicosapentaenoic acid were significantly lower in women who had caesarean deliveries versus vaginal deliveries [Ref # 22]. Drug class: Ophthalmic glaucoma agents. If untreated, they can eventually lead to vision loss. In the future, monolaurin or lauric acid may be regulated and used as an antiviral, antibacterial, or antifungal agent. Human breast milk is on average 6.2% lauric acid, and breastfeeding provides infants their first introduction to monolaurin. Healthline. Scientists hypothesize that it may inhibit the activity of gram-positive bacteria such as [8, 28, 29, 30, 18, 31]: Monolaurin might not be active against most gram-negative bacteria like Salmonella, which has a different kind of outer cell membrane than gram-positive bacteria [6]. WebThirty-two mixed-breed male and female cats were blocked by sex, arranged by body weight from greatest to least, and allocated to 4 groups of 8 (4 male, 4 female) cats, Through the addition of our exclusive Monolaurin Plus, we offer a fuller spectrum of the coconut monoglycerides than other forms of monolaurin currently in the market. Ezigbo, Veronica O., Mbaegbu Emmanuella A. It can be life-threatening in immunocompromised people. Another study in the Journal of Drugs in Dermatology suggested that monolaurin extracts may be potent against several bacterial species that can cause skin infections, including Staphylococcus aureus and Streptococcus spp, when studied in lab settings. Monolaurin has been listed as "Generally Regarded As Safe" by the FDA [Ref #15], stating "In accordance with 184.1(b)(1), the ingredient is used in food with no limitation other than current good manufacturing practice. Our bodyadds glycerol to other coconut acids, as well, and converts them into the monoglyceridesMonoCaprinandMonoMyristin. Pellets: Pellets may offer a high dose on the label, but they may pass though the digestive tract un-absorbed and may contain higher amounts of potentially stomach-irritating glycerol. She loves communicating science and empowering people to achieve their optimal health. "Monolaurin: Benefits, Dosage, and Side Effects". 10:271-85, 2001. Dr. Kabara discovered monolaurin and markets it under the brand name Lauricidin. Monolaurin is many times more effective than lauric acid at killing viruses and bacteria; however, researchers arent sure exactly how its formed in the human body. WebGlargine (Lantus), q 12 hr based on the estimated ideal body weight of the cat and BG levels: This equates to 1 U q 12 hr in the average cat. What is the suggested dose? There is no valid evidence to back them up. Kabara JJ, Vrable R. Antimicrobial lipids: natural and synthetic fatty acids and monoglycerides. NOTE:In dogs, the manufacturer recommends a starting dose of 0.5 U/kg q 24 hr. WebInstill 1 drop into the affected eye (s) every 6 to 8 hours as needed. According to a 2013 study, monolaurin is effective both in vitro and in living beings against certain strains of Staph infection. Additives (Pure Formula vs. Healthline only shows you brands and products that we stand behind. WebThere are two scenarios in which negative results may occur in infected cats. 1 INDICATIONS AND USAGE. A complete list of academic studies on monolaurin along with select excerpts (including official citations) are available on the Monolaurin Research Page. Manufacturing (Facility Location and Certifications): A GMP facility, FDA registered, and USA-made certifications provide a degree of confidence over non-certified manufacturing or foreign facilities. If more than one topical ophthalmic product is to be used, the different products should be instilled at least 5 minutes apart. According to this theory, when large numbers of infecting organisms die quickly, these microbes give off toxins as they die [55]. Pellets are relatively expensive per-jar and potentially inconvenient to transport / fit in pill organizers. A low-fat diet may also contribute to higher levels of lauric acid [Ref # 25], Nationality or Ethnicity: In a study of 50 breast milk samples from women in nine different countries, women from The Philippines had almost twice the amount of lauric acid present in their breast milk compared to women from Australia, Canada, China, Chile, Japan, Mexico, the United Kingdom, or the United States [Ref # 26], Supplementation of fatty acids: Eating oils high in lauric acid (like coconut oil) has been shown to increase the presence of that acid in breast milk within 6 hours of consuming and remain elevated for 10-24 hours [Ref # 27]. Putting it into soft pet foods will help them eat the pellets. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Lauric acid is a medium chain fatty acid which has been the subject of published research exploring the potential of the acid to disrupt various viruses, yeast and bacterial infections, skin conditions, among other ailments in lab settings [Ref #1, 2]. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Additionally, given that you've probably had it awhile, it might be prudent to look for EBV triggered antibodies which may be causing symptoms. Jonathan Ritter, PharmD, PhD (Pharmacology), Goat and cow milk (contain only a small percentage of lauric acid). As indicated earlier in the article, it is unknown what percentage of lauric acid actually converts to monolaurin in the body when consumed. Although this study did not use human participants, it did show monolaurins effectiveness at killing bacterial infection in mice. Their reviews do not represent the opinions of SelfHacked. Monolaurin and More does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. is a monoglyceride comprised of lauric acid and glycerol. Joe Cohen flipped the script on conventional and alternative medicine and it worked. (2007). Other studies suggest that monolaurin disintegrates the protective viral envelope, killing the virus [Ref #13]. Taking it with a hot beverage can make the taste worse. Monolaurin is available as minipellets that should be swallowed and not chewed. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Monolaurin research suggests it is able to inactivate lipid-coated viruses such as herpes, cytomegalovirus, influenza, and various pathogenic bacteria and protozoa in lab settings [Ref #1, 2, 3, 11, 12]. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. WebCats are more sensitive to furosemide than dogs. People take monolaurin supplements to encourage immune health and general wellness, but theres little scientific data to back up these claims. Most of the bacteria also did not display any resistance to the monolaurin. Most common hospital and foodborne infections have become resistant to the effects of traditional antibiotics, and people are dying of formerly treatable conditions. WebSo, thats something to be careful about. Lipids. Drug Interactions and Toxicity: Select one or more newsletters to continue. Ana has many years of experience in clinical research and health advising. Theres no clinical evidence whatsoever to support the use of monolaurin. Monolaurin has shown antibacterial and antiviral effects when examined in test tubes and culture dishes, which is referred to as in vitro testing. Food allergies are common, but serious allergic reactions to coconut are rare, even among people who are allergic to tree nuts. UltraLaurin - The Ultimate Monolaurin (7oz), Buy 3 or above Some people claim that monolaurin can trigger a die-off reaction by killing microbes in the body, but theres no scientific evidence to back them up. Monolaurin (also known as glycerol monolaurate) is a medium chain fatty acid formed from lauric acid. Haase AT, et al. Under 130 pounds: 1 scoop, 2 times daily. Powder: Monolaurin by nature has a strong soapy and bitter taste. An Antibacterial Skin Spray that contains the same monolaurin as well as If you have specific questions, consider the information in the Dosing Guide for Monolaurin. Over 130 pounds: 1 scoop, 3 times daily. SelfHacked does not endorse any specific product, service, or treatment. Our goal is to not have a single piece of inaccurate information on this website. Monolaurin has statistically significant in vitro broad-spectrum sensitivity against Gram-positive and Gram-negative bacterial isolates from superficial skin infections. Additionally, over 60% of mice survived when receiving a daily combination of origanum oil and monolaurin [5]. SelfDecode does not treat, diagnose or cure any conditions, This can cause some mild chills, flu or allergic type symptoms. In some experiments, the monolaurin extracts were more potent against these bacteria as compared to conventional antibiotics [Ref #31]. Eyres, L., Eyres, M. F., Chisholm, A., & Brown, R. C. (2016, March 5). Monolaurin research looked into the potential of this compound to affect Alzheimers disease, which has been linked to herpes infection [50]. All quotes below are taken directly (verbatim) from published studies and are not the opinion of this site. Pets:Also adjust based on a human adult weight. Cats 0.250.5 U/kg q 12 hr (not to exceed 3 U per cat). What kind of dosage should I be taking? Dermatitis,15(3), 109-116. No dosing guidelines can be established [38]. Inform June 2005; Volume 16 p386-7. Our website services, content, and products are for informational purposes only. (3) Sterile water q.s., if needed, to total 2 cc volume for cats 2.5 kg (5 lb) and over. The Task Force recognizes that clients are often cost-constrained. The research on monolaurin is limited. ALPHAGAN P (brimonidine tartrate ophthalmic solution) 0.1% or 0.15% is an alpha adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.. 2 DOSAGE AND ADMINISTRATION. The effect of hydrogenated fat in the diet of nursing mothers on lipid composition and prostaglandin content of human milk. So far, its effects have only been seen when tested in laboratories or on animals. Dr. Jon Kabara, who first reported on monolaurin and now markets it under the brand name Lauricidin, suggests that people age 12 and older start with 750 milligrams (mg) of monolaurin two to three times per day. Inform June 2005; Volume 16 p386-7. We do not aim to diagnose, treat, cure or prevent any illness or disease. 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Not aim to diagnose, treat, diagnose or cure any conditions, this cause..., over 60 % of mice survived when receiving a daily combination of origanum oil and daily! Research looked into the potential of this site in infected cats ( ophthalmic ) exactly as directed the. As compared to conventional antibiotics [ Ref # 13 ] of hydrogenated fat in the health industry and we exclusively! Nature has a strong soapy and bitter taste traditional antibiotics, and certified health and general wellness, serious! Script on conventional and alternative medicine and it worked chain fatty acid composition nine!